PWEALL - Design and Monitoring of Survival Trials Accounting for Complex
Situations
Calculates various functions needed for design and
monitoring survival trials accounting for complex situations
such as delayed treatment effect, treatment crossover,
non-uniform accrual, and different censoring distributions
between groups. The event time distribution is assumed to be
piecewise exponential (PWE) distribution and the entry time is
assumed to be piecewise uniform distribution. As compared with
Version 1.2.1, two more types of hybrid crossover are added. A
bug is corrected in the function "pwecx" that calculates the
crossover-adjusted survival, distribution, density, hazard and
cumulative hazard functions. Also, to generate the
crossover-adjusted event time random variable, a more efficient
algorithm is used and the output includes crossover indicators.